| Model: | - |
|---|---|
| Brand: | Creative Diagnostics |
| Origin: | Made In United States |
| Category: | Chemicals / Biochemical |
| Label: | Rabbit Anti-Human HR |
| Price: |
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| Min. Order: | - |
| Last Online:25 Nov, 2014 |
http://www.creative-diagnostics.com/Anti-Human-HRK-Antibody-2870-147.htm
Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL
