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Product Name: Trelagliptin

CAS No.: 865759-25-7

Information: DPP-4 inhibitor,long-acting and selective.

Description: Trelagliptin is a long acting inhibitor of dipeptidyl peptidase-4 (DPP-4).

Other Names: SYR-472, SYR472, SYR 472, Trelagliptin,

Chemical Name: 2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile

Canonical SMILES: CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCCC(C3)N

MF: C18H20FN5O2

MW: 357.3821

Purity: 99%

Type: Antidiabetic Agents

Grade Standard: Medicine Grade

Model Number: API-Trelagliptin

Solubility: Soluble in DMSO > 10 mM

Storage: Store at -20°C 

Brand Name: Huavet

Place of Origin: Shaanxi, China (Mainland)

General tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. 

Shipping Condition: Evaluation sample solution: ship with blue ice. All other available size: ship with RT , or blue ice upon request

Background: Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-daily. A once-weekly treatment, such as trelagliptin, would provide patients with a convenient treatment alternative and has the potential to improve treatment compliance.

Usage: Pharmaceutical Intermediates

Inventory status: in stock

Shelf life: 2 years

Sample: Available

COA (Certificate of Analysis): Available

MSDS (Material Safety Data Sheet): Available

HPLC Spectrum: Available

ISO: Approved

GC: Available

NMR (Nuclear Magnetic Resonance): Available

Packaging Details: 1g, 5g, 10g, 50g, 100g/bottle, 1kg/tin for trial order,25kg/drum for commercial quantity. Specific packing required by customer

Delivery Detail: Prompt shipment

Related Antibodies:

*DPP4 Antibody (89F4)

*DPP4 Antibody (68R3)

*DPP4 Antibody (46I2)

*DPP4 Antibody