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FDA Chitosan Oligosaccharide Feed Addictive Antibiotic Substitutes

【Antibiotics Introduction】

Antibiotics can promote the growth of animals, antibiotic additives are widely used in feed. In the aspect of improving animal production performance, the effect of antibiotics is incomparable to any other feed additives, and antibiotic additives can obtain 5-8 times profit. However, a large number of long-term use of antibiotics in feed does cause worrying problems: one is drug resistance; the other is residue.

Antibiotic residues not only affect the quality and flavor of animal products, but also are considered to be an important way for the transmission of drug resistance of animal bacteria to human beings. Because of this, the European Commission limits the use of antibiotics as feed growth additives. The research and development of natural non-toxic, efficient and cheap green feed additives to replace antibiotic products has become a research hotspot and development trend in the field of additives. Countries all over the world have invested a lot of human and financial resources in the research

【Antibiotic Substitutes-Chitosan Oligosaccharide】

In recent years, scientific research has found that chitosan oligosaccharide has no significant difference with antibiotics (chlortetracycline, Flavomycin) in improving animal growth performance, improving animal immune function and improving feed utilization rate, so it can be added to feed instead of these antibiotics

【Chitosan Oligosaccharide Instead Of Antibiotics】

Subjects:

1080 1-day-old Ross 308 commercial broiler cocks were divided into 6 treatments for 39 days.

The results show that: 1

Compared with the control group, the average daily gain and immune organ index of broilers fed the diet supplemented with 100-200 g / T chitosan oligosaccharides were significantly higher than those of the control group, the contents of IgA, IgG and IgM were significantly increased, the activity of GSH PX in serum was significantly increased, and the content of MDA was significantly decreased; the concentration of propionic acid and isobutyric acid in jejunum and ileum Chyme of broilers fed the diet supplemented with 200-300 g / T chitosan oligosaccharide was increased; compared with the control group, the results showed that the diet supplemented with 100-200 g / T chitosan oligosaccharide could significantly increase the content of propionic acid and isob There was no significant difference in growth performance and immune function of broilers fed with 100 ~ 200 g / T chitosan oligosaccharide.

Dosage s estion:

(1) Adding 200 g / T chitosan oligosaccharide to the diet can significantly improve the speed of weight gain and feed intake of broilers, and then increase their market weight; it can improve the content of serum immunoglobulin of broilers, enhance the body immunity, and improve the antioxidant capacity of serum and liver of broilers.

(2) Dietary supplementation of 100-200 g / T chitosan oligosaccharide significantly promoted the development of immune organs of broilers.

(3) Dietary supplementation of 100-200 g / T chitosan oligosaccharide could significantly improve the intestinal microecological environment of broilers, especially the ileal microflora.

(4) Adding chitosan oligosaccharide in broiler diet can replace part of antibiotics in feed, which provides scientific basis for non resistant breeding.