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Minoxidil is a kind of clinical oral medications for blood pressure, also known as long pressure Pp pyrimidine diamine step-down to determine blood min le, belong to the agent of potassium channels open, can directly relax vascular smooth muscle, small artery expansion has a powerful effect, make the peripheral resistance drop blood vessels dilate blood pressure to drop, and no influence on the capacity of the blood vessels, thus can promote the venous return At the same time, due to reflex regulation and positive frequency effect, can make the cardiac output and heart rate increase, but does not cause postural hypotension for clinical treatment of intractable hypertension and renal hypertension Also can be used to other severe high blood pressure, blood pressure medication the effect not beautiful, but you need to share in order to avoid water sodium retention, diuretic and beta blocker fungicides can allow it to increase curative effect, less adverse reaction Long-term use of minoxidil, there may be a side effect, the body hair it may slightly increase with the continued use of drugs, such as arm hair But generally within the acceptable range of oral adverse reactions mainly include: water and sodium retention caused by weight gain, lower limb edema reflex and sensory nerve stimulation caused by palpitation and arrhythmia hypertricosis and other topical preparations of adverse reactions mainly include: skin irritation, erythema itching and other dermatitis Although the absorption amount of topical preparations is very small, it cannot be excluded that it will have an impact on the condition of patients with a history of heart disease. It must be used with caution in patients with cerebrovascular diseases, heart failure, coronary heart disease, angina pectoris, myocardial infarction, pericardial effusion, renal dysfunction and other diseases not caused by hypertension, and it should be prohibited in patients with minoxidil allergy and pheochromocytoma