CAS 1370003-76-1 Yk-11 Sr9009
Product Description
Basic Info
| Melting point |
134-137°C |
| Boiling point |
564.4±50.0 °C(Predicted) |
| density |
1.22±0.1 g/cm3(Predicted) |
| storage temp. |
-20°C Freezer |
| solubility |
Chloroform (Slightly), Methanol (Slightly) |
| form |
Solid |
| color |
White to Pale Yellow |
| Uses |
YK-11 is a synthetic steroidal selective androgen receptor modulator (SARM).It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR. |
| Uses |
YK-11, is a selective androgen receptor modulator. It regulates myogenic differentiation of C2C12 myoblasts by follistatin expression; SARMs |
| Mechanism of action |
YK-11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when used at a concentration of 0.1 μM.1 It induces expression of the androgen receptor target genes FKBP51 and FGF18 in HEK293 cells when used at a concentration of 10 μM. YK-11 accelerates nuclear translocation of androgen receptors without inducing interaction between the androgen receptor N- and C-termini. In C2C12 cells, YK-11 (500 nM) increases expression of the myogenic regulatory factors MyoD, Myf5, and myogenin, as well as follistatin (Fst), and induces myogenic differentiation. |
Product Image
Img 1
Send Inquiry to this Member
Related Products of this Company
This member assumes full responsibility for the content of this listing. DIYTrade accepts no responsibility whatsoever in respect of such content.
To report fraudulent or illegal content, please
click here.
China Suppliers Quick Searching:
,
