Inositol, (of which the most prominent naturally occurring form is myo-inositol, cis-1, 2, 3, 5-trans-4, 6-cyclohexanehexol), is a carbocyclic polyol that plays an important role as the structural basis for a number of secondary messengers in eukaryotic cells, including inositol phosphates, phosphatidylinositol (PI) and phosphatidylinositol phosphate (PIP) lipids. It is found in many foods, in particular, in cereals with high bran content, nuts, beans, and fruit, especially cantaloupe melons and oranges. Inositol is not considered a vitamin itself because it can be synthesised by the body. Other naturally occurring isomers (though in minimal quantities) are scyllo-, chiro-, muco-, and neo-inositol. Other possible isomers are allo-, epi-, and cis-inositol. Myo-Inositol was classified as a member of the vitamin B complex (often referred to as vitamin B8), but was found to be synthesized by the human body (thus, declassifying it as a vitamin). Function Inositol as the basis for a number of signaling and secondary messenger molecules, is involved in a number of biological processes, including: Insulin signal transduction[3] Cytoskeleton assembly Nerve guidance (Epsin) Intracellular calcium (Ca2+) concentration control[citation needed] Cell membrane potential maintenance[citation needed] Serotonin activity modulation Breakdown of fats and reducing blood cholesterol[citation needed] Gene expression
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