Quick Details

• Classification: Herbicide
• CAS No.: 111991-09-4
• Other Names: Nicosulfuron
• MF: C15H18N6O6S
• EINECS No.: 111991-09-4
• Place of Origin: Shandong, China (Mainland)
• State: Liquid
• Purity: 40g/L SC
• Application: corn herbicides
• Brand Name: Yufull
• Model Number: 40g/L SC, 75% WDG, 80% WP

Packaging & Delivery

Packaging Details:	500ml, 1L bottle, 4L, 5L, 10L, 20L, 200L drum, or as requirements.
Delivery Detail:	About 15-20 days after confirm order.

Specifications

Nicosulfuron 4% SC
1. TC, 75% WDG, 40g/L SC,80% WP
2. High efficacy corn herbicides
3. Large markets share in Ukraine etc
 

Nicosulfuron 4% SC

Formulation types: 98%TC,75%WDG,75%WP,4%SC

Biochemistry:Branched chain amino acid synthesis (ALS or AHAS) inhibitor. Acts by inhibiting biosynthesis of the essential amino acids valine and isoieucine, hence stopping cell division and plant growth. Maize selectivity derives from selective metabolism (P450 mediated pyrimidine-5-hydroxylation, followed by conjugation with glucose).

Mode of action:Selective systemic herbicide, absorbed by the foliage and roots, with rapid translocation in xylem and phloem to the meristematic tissues.

Uses:Selective post-emergence control in maize of annual grass weeds including Setaria, Echinochtoa, Digitaria, Panicum, Lolium, and Avena spp., broad-leaved weeds including Amaranthus spp. and Cruciferae, and perennials such as Sorghum halepense and Agropyron repens. Applied at 35-70 g/ha.

Mammalian Toxicology  

Oral:Acute oral LD50 for male and female rats and mice >5000 mg/kg.

Skin and eye:Acute percutaneous LD50 for male and female rats >2000 mg/kg. Moderate eye irritant; not a skin irritant (rabbits); not a skin sensitiser (guinea pigs). The 75% formulation is not an eye irritant.

Inhalation:LC50 for rats (4 h) 5.47 mg/l.

Noel:In 28 d feeding trials on rats and mice, no adverse effect up to 30 g/kg diet.
/Other Non-mutagenic in the Ames test.

Toxicity:WHO (a.i.) III (Table 5); EPA (formulation) IV

Ecotoxicology         

Birds:Dietary oral LD50 for bobwhite quail >2250 mg/kg.
Dietary LC50 for mallard ducks and bobwhite quail >5620 ppm.

Fish:LC50 (96 h) for bluegill sunfish and rainbow trout >1000 mg/l.

Daphnia:LC50 (48 h) >1000 mg/l.

Algae:NOEC (96 h) for green algae 100 mg/l.

Worms:LC50 (14 d) for earthworms >1000 mg/kg.
Bees: LD50 (contact) >20 μg/bee; dietary LC50 (48 h) >1000 ppm. NOEC 500 ppm.

Evironmental fate                 

Plant:Degraded rapidly in maize, DT50 1.5-4.5 d. Residues <0.02 ppm in all crops. Hydrolysis of the sulfonylurea bridge to form the pyridine sulfonamide and pyrimidine amine, and hydroxylation on the pyrimidim ring, were the main metabolic pathways.

Animals:the goat, following a dose of 60 ppm, <0.1 ppm was fount in tissues and milk; therefore nicosulfuron and its metabotites do not bioaccumulate. Hydrolysis of the sulfonylurea bridge and hydroxylation were the main metabolic pathways.

Soil/Environment:

Soil DT50 (aerobic) 26 d (pH 6.1, 5.1% o.m., 25°C). In four sandy loams, Kd (25°C) 0.16 (pH 6.6, 1.1% o.m.) to q.73 (pH 5.4, 4.3% o.m.) Photoiysis DT50 (soil) 60-67 d; (water) 14-19 d (pH 5), 200-250 d (pH 7), 180-200 d (pH 9). Values from separate studies were: Soil DT50 24-43 d (20~C); DT50 80-143 d (20°C). Kd 0.05-0.7. In water, DT50 15 d (pH 5, 20°C).