Name:Bexarotene
Iupac name:
4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic
CAS Registry number:153559-49-0
Synonyms:
Targret;Targretin;Targretyn;
Appearance:white solid
Density:1.042 g/cm3
Solubilities:Insoluble in water and slightly soluble in vegetable oils and ethanol
In water, 9.5X10-4 mg/L at 25 deg C (est)
Color/Form:Off-white to white powder.

Usage:
Used as an antineoplastic. A selective retinoid X receptor (RXR) agonistBiomedical Effects and Toxicity
Pharmacological Action:
- Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.
Therapeutic Uses:
THERAP CAT: Antineoplastic
Bexarotene is indicated for the treatment of cutaneous manifestations of cutaneous T-cell lyphoma in patients who are refractory to at least one other prior systemic therapy.
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