Name:Agomelatine
Iupac name:N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
CAS Registry number:138112-76-2
Synonyms:
Thymanax;Valdoxan;Acetamide;
Appearance:white solid
Density:1.109g/cm3
Computed Properties:
Molecular Weight:243.30098 [g/mol]
Molecular Formula:C15H17NO2

Usage:
A melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytry.
Pharmacological Action:
Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
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