NAME: Rutin
SPEC.:NF11 95% DAB10 EP 98%
TEST METHOD: UV
PLANT SOURCE: Scphora japonica L.
CAS NO: 153-18-4
MOLECULAR FORMULA & MOLECULAR Mass: C27H30O16 610.52


CHARACTERISTIC: Yellow or yellow-green powder or very fine needle-like crystal, odorless, tasteless, in the air gradually becomes darker, heated to 185-192 c into a jelly-brown. Difficult to dissolve in cold water (0.0013%), soluble in hot water (0.55%), hot methanol (11.2%), cold methanol (1.0%), hot ethanol (3.5 percent), cold ethanol (0.36%) cold pyridine (8.5 %), soluble in alkaline, and acid precipitation. Insoluble in other organic solvents.

PHARMACOLOGY: Rutin, the glycoside form of quercetin, is a bioflavonol having aromatic trimeric heterocyclic structure. It is a naturally occurring pigment. It, chemically 3-[[6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl) -5,7-dihydroxy-4h-1-benzopyran-4-one, is a yellow to greenish crystalline powder melting at 190 c. Rutin is classified as vitamin p which increases the strength of the walls of the blood capillaries and regulates their permeability. Others classified as vitamin p are catechin, citrin, eriodictin, hesperetin, hesperidin, nobiletin, quercetin,sinensetin, and tangeretin. It is not a dietary essential but is known to have the effect on capillary disorders. It may also have an contribution to the total antioxidant activity and detoxifiers. It is also know to have pharmacological action as an anti-inflammatory, antihistaminic and antiviral agen.