Sarsasapogenin and its aglycones have rich biological activities and pharmacological effects. Numerous studies have shown that the saponins of Anemarrhena asphodeloides have many effects, such as treating Alzheimer's disease, neuroprotection, lowering blood sugar, enhancing immunity, anti-tumor, anti-osteoporosis, anti-coagulation, anti-aging, anti-inflammatory, and so on. And because Anemarrhena asphodeloides plays a significant role in Alzheimer's disease and neuroprotection, more and more scholars at home and abroad have paid attention to Anemarrhena asphodeloides.

[Chinese alias] Anemarrhena saponin; Sarsasapogenin

[English name] Sarsasapogenin; Parigenin

[CAS No.] 126-19-2

[Molecular formula] C27H44O3

[Molecular weight] 416.646

[Purity] 98% (HPLC)

[Character] This product is white powder.

[Plant source] The dried rhizome of Anemarrhena asphodeloides Bunge.

[Storage conditions] Store in airtight containers away from light, refrigerate or freeze for long-term storage. Long-term high temperature or light will cause structural changes of this product.

[Product packaging] 20mg~1g brown glass bottle; 1 kg/bag; 25 kg/barrel; It can meet a large number of demands from gram level to kilogram level.

Plant Origin
Liliaceous plant rhizoma anemarrhenae Anemarrhena asphodeloides Bunge. Dried roots

Description

[1] Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells.

[2]. Feng B, et al. Sarsasapogenin reverses depressive-like behaviors and nicotinic acetylcholine receptors induced by olfactory bulbectomy. Neurosci Lett. 2017 Feb 3;639:173-178.

[3]. Lim SM, et al. Timosaponin AIII and its metabolite sarsasapogenin ameliorate colitis in mice by inhibiting NF-κB and MAPK activation and restoring Th17/Treg cell balance. Int Immunopharmacol. 2015 Apr;25(2):493-503.
 

References

Shen S1, Zhang Y1, Zhang R2, Gong X3. Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells. Biochem Biophys Res Commun. 2013 Oct 26. pii: S0006-291X(13)01782-8. doi: 10.1016/j.bbrc.2013.10.101

[2].Feng B1, Zhao XY1, Song YZ1, Liang WN1, Liu JL2.  Feng B, et al. Sarsasapogenin reverses depressive-like behaviors and nicotinic acetylcholine receptors induced by olfactory bulbectomy. Neurosci Lett. 2017 Feb 3;639:173-178.

[3]. Lim SM, et al. Timosaponin AIII and its metabolite sarsasapogenin ameliorate colitis in mice by inhibiting NF-κB and MAPK activation and restoring Th17/Treg cell balance. Int Immunopharmacol. 2015 Apr;25(2):493-503.

Hongying Zhang

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