What is polydatin 98%

Polydatin (piceid), an active ingredient extracted from Polygonum cuspidatum, is a stilbenoid glucoside of resveratrol. A sugar molecule is jointed to the resveratrol structure, making polydatin more bioactive and powerful in antioxidant and anti-aging potency.

Resveratrol includes trans-resveratrol and cis-resveratrol. Like resveratrol, there are two kinds of polydatin derivatives: trans-polydatin and cis-polydatin. The bioactivity of trans-isomers is much higher than that of cis-isomers. There are two CAS number available for polydatin, one is 65914-17-2 from Sigma-Aldrich, and the other is 27208-80-6 from Wikipedia (as piceid). Scientific literatures, references, documents use piceid more often while in dietary supplement industry polydatin is preferred. If not specified, all the polydatin and piceid mentioned below will be trans-polydatin.

Polydatin VS Resveratrol (conversion and comparison)
Trans-resveratrol is one of the major metabolites of polydatin. After oral administration in humans, Polydatin (Piceid), 3,4,5-trihydroxystilbene-3-beta-D-glucoside, is hydrolyzed into trans-resveratrol, trans-resveratrol-3-O-glucuronide in the small intestine. As a result, polydatin dramatically increases the concentration and half life of resveratrol and its other metabolites in blood plasma and tissues, making resveratrol over 1,000 times more concentrated in the tissues of animals than is the case with the same metabolites of resveratrol.

Once the polydatin enters the bloodstream the sugar molecule is cleaved off, leaving the resveratrol. Polydatin allows resveratrol to skip phase I metabolism and enter into the blood stream more readily. This in turn means that the glucoside of resveratrol is absorbed at a different rate to standard trans-resveratrol, thereby effectively increasing the half-life and the potency of the resveratrol， which provides a bioavailability of polydatin 2x to 5x longer than resveratrol.

Benefits of taking polydatin supplements

Polydatin is regarded as one of the best supplements in the world for its anti-aging benefits. Polydatin has all the benefits that resveratrol has, such as Anti-aging, Anti-Cancer, cardiovascular support, regulate estrogen level, and weight loss. Polydatin itself is anti-viral, anti-fungal, anti-inflammatory, and has been used in modern China for more than 50 years. Trans-polydatin activates genes which repair and support cell functions, providing many supports for better sleep, more energy, lower sugar, and weight management benefits.
The key benefits of polydatin supplements are listed as below:
1.Polydatin and anticancer;
2.Polydatin has effect on cardiovascular system;
3.Polydatin own the nourishing and protecting liver;
4.Polydatin has the usage of antibacterial and antifungal;
5.Polydatin has impact on the metabolism of bone issue;
6.Polydatin own the effective of antioxidant and quench free-radicals.

Where to buy high quality polydatin raw ingredient?
Resveratrol series ingredients are Herb Nutritionals Co., Ltd’s main products. There are around 5 resveratrol manufacturers here in China, while only one factory who really manufactures polydatin raw materials since the demand for polydatin is not as huge as resveratrol. Most Chinese export companies are suppliers of polydatin, and their prices are relatively high. We have readily stock of trans-polydatin 98% 200kg each month, certificate of analysis, MSDS, and other documents are available for your reference.