Indentification:

Product Name: Diosmin
Synonym: Barosmin, Buchu resin, Daflon
Specification:EP7,90:10
CAS: 520-27-4
Chemical Name: 7-{[6-O-(Deoxy-α-L-mannopyranosyl)-D-glucopyranosyl]oxy}-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Molecular Formula: C28H32O15

Molecular Weight: 608.54

Description:

Diosmin is greyish-yellow or light yellow hygroscopic powder,practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides. Melting point is 275-277 °C when purity is 95% tested by HPLC.

Indications: 
   -   The same effect with vitamin P which has a better effect on lowering permeability of capillary than pyrocatechin hydrate, hesperidin, quercetin and rutin. 
   -   The same effect with vitamin C2 which can increase resistance of capillary and reduce vitamin C elimination in adrenal gland.
   -   Anti-inflammatory: intraperitoneal injection, with a detumescence effect on vola pedis edema which caused by Carragenan. ED50 at 100mg/kg.
   -   Low toxicity, for the treatment of capillary frangibility. Dosage: oral administration of LD50 at 10g/kg, intraperitoneal injection of LD50 at 4g/kg.

Other Products in Benepure:

1, Natural Botanical Extract and derivatives:

Grape Seed Ext., Grape Skin Ext.,Hesperidin, Hidrosmin,Diosmin, Hesperidin Methylchalcone, Methyl Hesperidin, Citrus Bioflavonoids, Diosmin+Hesperidin 9:1, Naringin, Neohesperidin, Neohesperidin Dihydrachalcone, Naringin Dihydrachalcone, Rutin, Troxerutin, Quercetin, Resveratrol, Soy Isoflavones, Baicalin, Oleanolic Acid,  Bilberry Ext(Series), Ginkgo Biloba Ext., Green Coffe Bean Ext., Epimedium Ext., Green Tea Ext., Black Tea Ext., Milk Thistle Ext., Red Clover Ext., Gurarana Ext., Hoodia Ext., Olive Leaf Ext., Kava Ext., Yucca Ext., Kelp Ext.,Saw Palametto Ext., Marigold Exrtact(Lutein), Passion Flower Ext., Reishi Mushroom Ext. Tribulus Terrest Ext.,St. John's Wort Ext., Gotu Kola Ext......and so on...

2, APIs.:

Donepezil HCL,Tianeptine Sodium,Glycyl-L-Glutamine,Glycyl-L-Tyrosine,Clopidogrel sulfate,Ozagrel,Mildronate,Articaine hydrochloride,Prilocaine Base,Prilocaine HCL,Tetracaine Base,Tetracaine HCL,Lidocaine hydrochloride,Mepivacaine Base,Mepivacaine HCL,Pramoxine HCL,Dibucaine(Cinchocaine) Base,Dibucaine(Cinchocaine) HCL,Levobupivacaine HCL,Bupivacaine HCL,Ropivacaine Mesylate,Ropivacaine HCL,D-cycloserine,Brinzolamide,Medetomidine hydrochloride,Dexmedetomidine hydrochloride,Linezolid,Levodropropizine,Oteracil potassium

Gimeracil;CDHP,Esomeprazole sodium,Esomeprazole magnesium trihydrate,Troxipide,Ulipristal Acetate,Foscarnet Sodium

Levocetirizine Dihydrochloride,Loratadine,Policresulen intermediates, m-cresol sulfonic acid and formaldehyde ,Sevelamer HCl,Cephalotaxin,Cabazitaxel,Tafluprost,Posaconazole,Isavuconazonium sulfate,Isavuconazonium sulfate hydrochloride,Nintedanib Ethanesulfonate Salt,Alcaftadine ,Olaparib,Pamoic acid,Sofosbuvir,Entresto(LCZ-696),Veliparib,Mereletinib mesylate(AZD9291),Obeticholic Acid,OMarigliptin (MK-3102),Rolapitant,Dasatinib monohydrate,Gefitinib,Erlotinib hydrochloride,Sorafenib tosylate,Pregabalin,Linezolid,Sitagliptin phosphate monohydrate,Sitagliptin,Linagliptin,Sunitinib Mablate,Epavudine,Saxagliptin,Ticargrelor,Apixaban,Rivaroxaban,Pramipexole dihydrochloride,Lapatinib ditosylate,Dabigatran etexilate Methanesulfonate

3, Intermediates: