AI0026 Goserelin Acetate Ph. Eur.

Molecular Formula：

C59H84N18O14

Relative Molecular Mass：

1269.43 g/mol

CAS-Number：

65807-02-5 (net), 145781-92-6 (acetate)

Long-term Storage：

-20 ± 5°C

Synonym：

(D-Ser(tBu)6,Azagly10)-LHRH

Sequence：

Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2

acetate salt

Fields of Application：

Advanced hormone-dependent prostate cancer

Advanced hormone-dependent breast cancer

Endometriosis

Uterine myoma

Use in reproductive medicine

Active Substance：

Goserelin Acetate is a potent GnRH (LHRH) agonist. After a transient increase, continuous administration of goserelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.