Product Profile:

[Product Name]:  Pomegranate Bark Extract Powder/Ellagic Acid 
[Botanical Source]: Punica granatum L.
[Part Used]: Peel and seed
[Active Ingredient]:
Ellagic Acid: 40%, 50%, 90% (HPLC) 
Polyphenols: 40%,  (UV)
Punicalagins: 20%, 30%, 40%, (HPLC)
[Appearance]: Brown grey fine powder
Ellagic acid: C14H6O8; 
Punicalagins: C48H28O30
Ellagic acid: 476-66-4;
Punicalagins: 65995-63-3

The pomegranate (Punica Granatum L.) is packed with healthy anti-oxidants and anti-inflammatory agents with healthful benefits. The potent antioxidant activities of pomegranate are attributed to its phenolic compounds including punicalagin. Punicalagin is a water soluble ellagitannin with high bioavailability. It is found in forms alpha and beta in pomegranate. And not only does punicalagins offer a powerful kick of antioxidant properties on their own, it can be hydrolyzed into smaller phenolic compounds such as ellagic acid in vivo where one potential mechanism is hydrolysis across the mitochondrial membrane of cultured human colon cells.

Function:

Ellagic Acid, the active ingredient extracted from Punica granatum L., has the following functions:

1) Anti-cancer and anti-mutation. It has been proved to be an effective anti-carcinogen upon carcinoma of rectum and colon, esophageal carcinoma, liver cancer, lung cancer, carcinoma of tongue and skin.

2)Restrain to human immunodeficiency virus (HIV) and many kinds of microbe and virus.

3) Antioxidant, coagulant, descenting blood pressure and sedation.

4) Treat kinds of symptoms caused by high blood sugar, hypertension.

5) Resist to atherosclerosis and tumour.

6) Resist to antioxidance, senescence inhibition and skin whitening.

Application:

(1)Applied in pharmaceutical field, it is usually made into capsule to prevent cancer, lower blood pressure and resist oxidation.
(2)Applied in food field, it is usually used as food antioxidants.
(3)Applied in cosmetic field, it mainly used in whitening, dispeling spot, anti-wrinkle.

Dosage Information

In the most significant clinical studies to date, a daily dose of 78 mg of punicalagins yielded such remarkable benefits as reversing atherosclerosis, reducing high blood pressure, and preventing the adverse cardiovascular consequences of diabetes. Moreover, an important clinical study demonstrated that 280-375 mg of punicalagins per day halted the progression of prostate cancer in men who had failed conventional therapy.26 Life Extension thus recommends 78 mg of punicalagins per day for cardiovascular protection.

pomegranate bark extract powder should not be used by pregnant and nursing women, and overuse (many times the recommended dosage) may cause cramps, vomiting and diarrhea. Pomegranate fruit should not be taken if you have diarrhea, and in Traditional Chinese Medicine (TCM).