Introduction

Serrapeptase, which is a high-yield strain of Serratia, is extracted by deep submerged fermentation. This product is widely used in the medical field and is used as an alternative medicine in many countries (such as Japan) and has a long Application history.

Pharmacological Action

(1) Anti-inflammatory, swelling effect: 1 Inflammatory model of rats with thermal burns, vascular hyperpermeability can be inhibited after oral administration; 2 Oral can inhibit inflammatory edema of rat skin induced by anti-rat serum, It can inhibit cross-dish gum, dextran and serotonin. Rat inflammatory edema caused by various inflammatory substances such as bradykinin; 3 has strong ability to decompose inflammatory peptide bradykinin in vitro; 4 has strong solvency for fibrin and fibrin.

(2) Promote the sputum, the dissolution and excretion of the concentrated solution: 1 for patients with chronic paranasal sinusitis, the dry matter weight in the nasal sputum is reduced, the viscosity is decreased; 2 for rabbits exposed to sulfur dioxide gas and suffering from subacute bronchitis. The viscosity of the mash is significantly reduced.

(3) The role of promoting the displacement of antibiotics to the lesion: for patients with chronic paranasal sinusitis, it can promote the migration of ampicillin to the maxillary sinus.

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