Estradiol valerate is the valerate of natural estradiol, which has the pharmacological effect of estrogen, can promote and regulate the normal development of female genital canal and side sexual characteristics, and participate in the regulation of ovarian axis function
  Estradiol valerate is a female estrogen hormone. It works by replacing natural estrogens in a woman who can no longer produce enough estrogen.It works for advanced prostate cancer by antagonizing male hormones.

Function:
 1 Estradiol valerate is anti estrogen steroids which is used in Hormone Replacement Therapy in postmenopausal women who have had a hysterectomy Estradiol valerate contains a hormone which is similar to the hormone oestrogen that is produced by the body. When women go through the menopause, levels of oestrogen become low. This leads to symptoms such as hot flushes, night sweats and dryness of the vagina. Estradiol valerate helps to replace the low levels of oestrogen which may help to relieve the symptoms of the menopause. This is known as hormone replacement therapy.
 2 Treating certain symptoms of menopause (eg, hot flashes, vaginal itching, burning, or dryness). It is used to treat low levels of estrogen caused by certain conditions. It may be used to treat certain types of prostate cancer (advanced androgen-dependent). It may also be used for other conditions as determined by your doctor.