Bitter almond extract is based on the dried ripe seeds of mountain apricot PrunusarmeniacaL.var.ansuMaxim. of Rosaceae, Siberian apricot PrunussibiricaL., Northeast apricot Prunusmandshurica (Maxim.) Koehne or apricot PrunusarmeniacaL.

Bitter almond is also known as mountain apricot, bitter almond, apricot kernel, apricot kernel, almond, northern almond. The dried seeds are slightly flattened in the shape of a partial heart, with an acuminate tip and asymmetric left and right. Seed coat reddish brown or dark brown, from the base to the upper end of the scattered brown stripes, the surface has a fine longitudinal wrinkles; tip with inconspicuous bead hole, its lower lateral ridges, there is a light-colored prismatic seed umbilicus, the joint is located in the bottom concave part, from the joint to the seed umbilicus, there is a darker color longitudinal line, that is, the seed ridge, the seed coat is thin, there are two creamy white fat cotyledons, rich in oil, the middle of the joint surface, there are often gaps, radicle is located in Its tip, born at an altitude of 250 ~ 400 meters in the sunny slope of mixed wood forest on fixed dunes, produced in Beining, Fuxin, Jianping, Lingyuan, Jinzhou and other cities and counties. Almonds have sweet and bitter, cultivated apricot produced almonds sweet more, the wild is generally bitter. From the original plant, bitter almonds from Siberian apricot, Liao apricot and wild mountain apricot processing, mainly produced in the northeast of China, often referred to as the north almond, referred to as the north apricot; sweet almonds are processed by Batan apricot, the taste is more sweet, for easy distinction with the bitter almond, also known as the south apricot. Bitter almonds are bitter, good at lowering the gas, its asthma and cough relief is reliable. The sweet almond is inclined to moisten and nourish the lung, the effect is more moderate, its laxative and laxative function is more than the bitter almond, applicable to the lung deficiency cough or constipation and other diseases. Bitter almond is bitter, warm in nature, with small poison, entering the lung and large intestine meridian, with cough, asthma, laxative and laxative functions. Sweet almond is sweet in taste, flat in nature, non-toxic, moistens the lung and broadens the stomach, dispels phlegm and relieves cough.

Pharmacological effects

1. on the respiratory system of bitter almond extract has the effect of diastolic bronchial smooth muscle, relieve the spasm of bronchial smooth muscle, cough and asthma expectorant effect. The main mechanism is the slow decomposition of bitter amygdalin in the body, producing a trace of hydrocyanic acid, the respiratory center is sedative, so that the respiratory movement tends to quiet and achieve the cough, asthma; may also be due to low concentrations of hydrocyanic acid inhibit the oxidative metabolism of the carotid body and aortic body, resulting in deepening of reflex respiration, so that the sputum is easy to discharge.

2. The effect of bitter amygdalin on the immune function is promoted by intramuscular injection of bitter amygdalin on the proliferation of splenocytes in mice, which can promote the proliferation of T lymphocytes in the spleen of mice by mitogen. Bitter amygdalin can enhance the activity of mouse spleen NK cells in mice.

3. Antitumor effectThe crude extract of hot water extract of bitter almond has inhibitory effect on human cervical cancer cell culture strain JIC-26. The ingestion of bitter almond (freely ingested) to mice inhibited the growth of Ehrlich ascites carcinoma and prolonged the survival period. Give mice oral or intraperitoneal injection of bitter almond extract, the inhibition rate of S180, liver cancer solid tumors reached more than 60%, bitter amygdalin can also significantly prolong the survival time of rats inoculated with W256 sarcoma.

4. The effect on the digestive system bitter almond glycoside hydrolysis product benzaldehyde in vitro and in healthy people or ulcer patients, can inhibit the digestive function of pepsin, so it has anti-ulcer effect. Almond fat oil in the intestine to play a lubricating laxative effect.

5. Anthelmintic, antibacterial effect bitter almond oil in vitro test on roundworms, earthworms, pinworms, hookworms, etc. have a killing effect, and can inhibit typhoid and paratyphoid bacteria. Clinical application also shows that it has effect on roundworm, pinworm and hookworm.

6. Other effects almond decoction can produce obvious and lasting hypotensive effect when given to cats by sedation. It can also dilate coronary arteries and increase coronary blood flow.
 

Company Introduction
Address: Room 202, Building B8, Huanchuang Enterprise Square, Lugu Street, Yuelu District, Changsha City, Hunan Province
Website: http://www.staherb.com/
Business scope: Biotechnology, research and development of plant extracts (can be used in the field of pharmaceutical and health products, cosmetics, feed additives and biological pesticide production and development)
Main products: Eucommia extract - chlorogenic acid (5%-98%), ursolic acid (25%-98%), corosolic acid (1%-98%), bitter amygdalin (50%-98%), epimedoside (10%-98%) and other standardized high-purity plant extracts.

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