CAS 1370003-76-1 Yk-11 Sr9009

CAS 1370003-76-1 Yk-11 Sr9009
Model:chem
Brand:hlx
Origin:Made In China
Category:Chemicals / Pharmaceutical Chemicals
Label: -
Price: US $100 / pc
Min. Order:1 pc
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Product Description

Basic Info

Brand Name HLX
Product Name yk11
CAS 1370003-76-1
yk11 Chemical Properties
Melting point  134-137°C
Boiling point  564.4±50.0 °C(Predicted)
density  1.22±0.1 g/cm3(Predicted)
storage temp.  -20°C Freezer
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
color  White to Pale Yellow
yk11 Usage And Synthesis
Uses YK-11 is a synthetic steroidal selective androgen receptor modulator (SARM).It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR.
Uses YK-11, is a selective androgen receptor modulator. It regulates myogenic differentiation of C2C12 myoblasts by follistatin expression; SARMs
Mechanism of action YK-11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when used at a concentration of 0.1 μM.1 It induces expression of the androgen receptor target genes FKBP51 and FGF18 in HEK293 cells when used at a concentration of 10 μM. YK-11 accelerates nuclear translocation of androgen receptors without inducing interaction between the androgen receptor N- and C-termini. In C2C12 cells, YK-11 (500 nM) increases expression of the myogenic regulatory factors MyoD, Myf5, and myogenin, as well as follistatin (Fst), and induces myogenic differentiation.
Payment Terms:TT ALI
CAS 1370003-76-1 Yk-11 Sr9009 1

Member Information

Qiu Hao lai Xin new material technology co., ltd
Country/Region:He Bei - China
Business Nature:Manufacturer
Phone:83428936
Contact:Li Wei (manager)
Last Online:30 Nov, 2022
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