Pazopanib Hydrochloride is the hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived  receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.