STOCK STOCK STOCK Tamoxifen

Model:	BTO-1006
Brand:	BTO
Origin:	Made In China
Category:	Chemicals / Pharmaceutical Chemicals
Label:	breast tissue via , antineoplastic agent
Price:	US $10 / pc
Min. Order:	10 pc

Inquire Now

Product Description

Name:Tamoxifen

CAS:10540-29-1

Type:antineoplastic agents

Purity:99%

Packaging detail: in aluminum foil packing

Application: anti breast cancer

Chemical name	(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)phenoxy)-n,n-dimethylethanamine
Molecular Formula	C26H29NO
Molecular Weight	371.51
Purity	99% min by HPLC
Appearance	White crystalline powder

Usage

Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, hence tamoxifen may be characterized as a mixed agonist/antagonist. It has been the standard endocrine (anti-estrogen) therapy for hormone receptor-positive early breast cancer in pre-menopausal women, although aromatase inhibitors have been proposed.

Some breast cancer cells require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.