Psoralen
 Psoralen   CAS :66-97-7      Molecular Weight：186.166   Formula：C11H6O3

Purity:                  HPLC98%
 Appearance：   Off-white powder
Test Method：    HPLC; Mass;NMR
Usage:                 For laboratory research use only,not for human or diganostic use。
Package              20mg~1g per bottle。
Storage：           Store in a well closed container, protected from air and light.
Prepare and use solutions at the time of testing. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

Plant Origin

Psoralea corylifolia L. Fruit drupaceous Psoralea p. rupacea Bunge

Description

[1]psoralen promotes cartilaginous extracellular matrix (ECM) synthesis, as well as increased cartilaginous gene expression, and it may be a useful bioactive component for activating the cartilaginous cellular functions of chondrocytes.

[2]Psoralen and isopsoralen have growth inhibitory effects on transplanted tumor in nude rats with osteosarcoma, and can induce tumor cell apoptosis or necrosis, without significant toxic effects.

[3]The results of this study s est that psoralen is a bone-modifying agent and a potential therapeutic to treat patients with bone metastases.

References

[1]. Xu K, et al. Psoralen activates cartilaginous cellular functions of rat chondrocytes in vitro. Pharm Biol. 2014 Dec 4:1-6.

[2]. Lu H, et al. Isolation and purification of psoralen and isopsoralen and their efficacy and safety in the treatment of osteosarcoma in nude rats. Afr Health Sci. 2014 Sep;14(3):641-7.

[3]. Wu C, et al. Psoralen inhibits bone metastasis of breast cancer in mice. Fitoterapia. 2013 Dec;91:205-10.

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