Model: | API-Aripiprazol |
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Brand: | Huavet |
Origin: | Made In China |
Category: | Chemicals / Organic Chemical Materials / Pharmaceutical Chemicals |
Label: | Aripiprazole , 129722-12-9 , ABILIFY |
Price: |
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Min. Order: | 1 gram |
Product Name: Aripiprazole
CAS No.:129722-12-9
Information: Antipsychotic
Chemical Name 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Other Names: ABILIFY; ABILITAT; ARIPIPRAZOLE; ARIPIPRAZOLE-D8; OPC 14597; OPC 31;
7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone; OPC-14597, OPC-31,; 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one; Arpiprazole; Alipiprazole; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril; Abilify-d8; Abilitat-d8; OPC 14597-d8; OPC 31-d8-
Canonical SMILES: C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
MF: C23H27Cl2N3O2
MW: 448.39
Solubility: Soluble in DMSO > 10 mM
Storage: Store at -20°C
General tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition: Evaluation sample solution: ship with blue ice. All other available size: ship with RT , or blue ice upon request
Background: Aripiprazole is a novel and atypical antipsychotic [1].
Aripiprazole has been found to be a dopamine-serotonin system stabilizer with potent partial agonist activity at dopamine D2 and 5-HT1A receptors and antagonist activity at 5-HT2A receptors. In addition, aripiprazole has been reported to label with the agonist [125I]7-OH-PIPAT and with the antagonist [3H]spiperone with 0.34±0.02nM and 0.70±0.22nM, respectively. Besides, aripiprazole has been revealed to dose-dependently and potently inhibit the increase in cAMP accumulation stimulated by forskolin in CHO cells and HEK-293 cells. Other results have also been reported that aripiprazole completely inhibited the increase GTPase activity stimulated by the D2 receptor agonist quinpirole in rat striatal membranes [1].
Purity: 99.0%min
Appearance: Off-white or white crystal
Assay: 99.0%min
Melting Point:136-142℃
Chloride:≤0.02%
Sulphated Ash:≤0.1%
Heavy Type: Central Nervous System Agents
Grade Standard: Medicine Grade
Metals:≤10ppm
Model Number: API-Aripiprazole
Brand Name: Huavet
Place of Origin: Shaanxi, China (Mainland)
Usage: Pharmaceutical Intermediates
Inventory status: in stock
Shelf life: 2 years
Sample: Available
COA (Certificate Of Analysis): Available
MSDS (Material Safety Data Sheet): Available
HPLC Spectrum: Available
ISO: Approved
GC: Available
NMR (Nuclear Magnetic Resonance): Available
Packaging Details: 1g,5g,10g,50g,100g/bottle, 1kg/tin for trial order,25kg/drum for commercial quantity. Specific packing required by customer
Delivery Detail: Prompt shipment
Shaanxi Huavet Chemical Co.,Ltd. | |
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Country/Region: | Shaan Xi - China |
Business Nature: | Manufacturer |
Phone: | 13891930268 |
Contact: | Mr.Gordon Dong (Sales Manager) |
Last Online: | 23 Oct, 2024 |