Product Name: Lenalidomide (CC-5013)

CAS No.:191732-72-6

Information: Antineoplastic agent, inhibits angiogenesis

Description: Lenalidomide (CC-5013) is an inhibitor of TNF-α secretion with IC50 of 13 nM.

Other Names: Revlimid,IMiD3,CC 5013,CDC-501,CDC 501

Chemical Name: 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione

Canonical SMILES: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N

MF: C13H13N3O3

MW: 259.26

Purity: 99%

Grade Standard: Medicine Grade

Type: Antineoplastic Agents

Model Number: API- Lenalidomide

Solubility: Soluble in DMSO > 10 mM 

Storage: Store at -20°C 

General tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. 

Shipping Condition: Evaluation sample solution : ship with blue ice. All other available size: ship with RT , or blue ice upon request

Background: Lenalidomide (also known as CC-5013), an oral derivative of thalidomide, is an antineoplastic agent exhibiting antitumor activity through a variety of mechanisms, including immune system activation, angiogenesis inhibition, and direct antineoplastic effects. It has been extensively studied for the treatment of multiple myeloma and myelodysplastic syndrome as well as lymphoproliferative disorders including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma. According to recent studies, Lnalidomide promotes and restores immune system function in CLL patients by inducing an overexpression of costimulatory molecules in leukemic lymphocytes to restore the humoral immunity and immunoglobulins production as well as improving the ability of T cells and leukemic cells to form synapses with T lymphocytes.

Brand Name: Huavet

Place of Origin: Shaanxi, China (Mainland)

USAGE: Pharmaceutical Intermediates

Inventory status: in stock

Shelf life: 2 years

Sample: Available

COA (Certificate of Analysis): Available

MSDS (Material Safety Data Sheet): Available

HPLC Spectrum: Available

ISO: Approved

GC: Available

NMR (Nuclear Magnetic Resonance): Available

Packaging Details:1g,5g,10g,50g,100g/bottle, 1kg/tin for trial order,25kg/drum for commercial quantity. Specific packing required by customer

Delivery Detail: Prompt shipment

 

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