| Product Name: |
Fish Apolipoprotein E(APOE) ELISA kit
|
| Product Type : |
ELISA Kit |
| Code : |
CSB-EL001936FI |
| Size : |
96T,5×96T,10×96T |
| Abbreviation : |
APOE |
| Protein Biological Process 1 : |
Transport |
| Alias : |
AD2, LDLCQ5, LPG, MGC1571, apolipoprotein E3 |
| Species : |
Fish |
| Protein Biological Process 3 : |
Lipid transport |
| Assay Time : |
1-5h |
| Sample Volume : |
50-100ul |
| Detection Wavelengt : |
450 nm |
| Availability : |
5-7 working days |
| Research Area : |
Signal Transduction |
| Target details : |
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
| HGNC : |
613 |
| RGD : |
2138 |
| MGI : |
88057 |
