a.Milk thistle P.E. provides hepatocellular protection by stablizing hepatic cell membranes.

b.Milk thistle P.E. alters the structureof the outer cell membrane of the hepatocytes in such a way as to prevent the penetration of the liver toxins into interior of the cell.

c.Silymarin has the stimulation effect on nucleolar polymerase A results in an increase in ribosomalprotein synthesis,and thus increase the regenerative ability of the liver and formation of new hepatocytes.

d.Silymarin as other actions include interruption of enterohepatic recirculation of toxins and regeneration of damaged hepatocytes.