The microporous membrane filter is mainly used for the filtration of mobile phase and samples during the chromatographic analysis, especially for preventing chromatographic column and infusion pump line system and sample valve from pollution. They are widely used for gravimetric analysis, microanalysis, colloid separation and sterility test. The filer membrane made of different materials, such as polyetherdsulfone, nylon6, estron and polytetrafluoroethylene, etc. can be provided.