Microporous Membrane Filter

Instructions

The microporous membrane filter is mainly used for the filtration of mobile phase and samples during the chromatographic analysis, especially for preventing chromatographic column and infusion pump line system and sample valve from pollution. They are widely used for gravimetric analysis, microanalysis, colloid separation and sterility test. The filer membrane made of different materials, such as polyetherdsulfone (PES), nylon6, Nylon66 MCE and polytetrafluoroethylene (PTFE), PVDF etc. can be provided.

Nylon66 (from PALL)

High quality nylon66 membranes are suitable for filtering aqueous solutions and most organic solvents. The membranes are suitable for use with a wide range of biological preparations and can be used where other membranes are unsuitable or difficult to use.

Nylon66 membranes are hydrophilic, eliminating the need for wetting agents that could be extracted when filtering aqueous solutions. The membranes are flexible, durable and tear resistant, and can be autoclaved at 121ºC. This kind of membrane is imported from England.

 

Applications

• Filtration of aqueous and organic mobile phases
• Vacuum degassing

Filtration of tissue culture media, microbiological media, buffers and solutions

Data

	Nylon 66  0.45	Nylon 66  0.2
Membrane thickness（um）	114.8-170.2	139.7-177.8
Bubble Point	2.21-2.48	3.52-3.86

PES (from PALL)

Polyethersulfone (PES) membranes are hydrophilic, low protein binding and stable in alkaline pH. Available in a 0.8µm pore size, the PES membrane is recommended for aqueous applications and for biological samples. They are also an alternative choice for users requiring a filter that exhibits extremely low protein binding characteristics. This kind of membrane is imported from MEMBRANA company in Germany.

Data

	PES  0.45	PES 0.2
Membrane thickness（um）	114.3-165.1	129.5-162.6
Bubble Point	2.48-3.31	3.65-4.76
Typical Water Flow Rate(ml/min/cm2,0.7bar  10Psi)	38-100	19.3-34.6

 

PTFE (from PALL)

PTFE membranes are particularly suitable for preparing samples for HPLC analysis. The hydrophobic nature of the membrane also has applications for air and gas sterilization. The membrane is laminated onto a non-woven polypropylene support web for improved strength and handling and can be used at temperatures up to 150ºC.

PTFE is the membrane of choice for use with the aggressive solvents, liquids and gases that can attack other membranes. It is resistant to most acids, alkalis and solvents.

Applications

One of the major applications for the PTFE filter is the clarification of corrosives, solvents and aggressive fluids. This includes the important requirement in HPLC analysis for sample filtration where any solid particles can cause permanent damage to the column. The 0.45µm pore size is normally used.

Data

	PTFE  0.45	PTFE 0.2
Membrane thickness（um）	198.1-269.2	203.2-330.2
IPA Bubble Point (psi)	6.1-19.6	16.0-26.0
Mullen Water Breakthrough (psi)	≥30.0	≥80.0

Mixed Cellulose Ester (MCE)

Navigator MCE membrane filters are modified to offer researchers the lowest binding filters available. Due to the extremely low binding characteristics, these filters provide higher throughputs than competitive offerings and reduce filter changes when filtering proteinaceous solutions.

Because of their unique strength and extremely low binding characteristics, MCE membranes are ideal for protein and enzyme filtrations, tissue culture media sterilization, cold sterilization, biological fluid filtration and other filtration applications where maximum recovery of proteins is critical. 

Features and Benefits:

• Lowest binding material available
• Hydrophilic
• High throughput
• Strength and dimension stability
• Uniform pore structure

Applications:

• Protein and enzyme filtration, sterilization
• Biological fluid filtration sterilization
• Tissue culture media sterilization
• Diagnostic cytology
• Receptor binding studies

·       Enhanced recovery of fastidious gram positive organisms                                                                                      Data(Mixed cellulose Ester 0.45um)

Thickness:                             100-150 μm

Bubble point (in water)                   0.23-0.3 bar

Transmembrane flow (water, 25ºC)        34-48 ml/min cm2

Hydrophilic PVDF (Polyvinylidene Fluoride)

    Hydrophilic PVDF (Polyvinylidene Fluoride) membranes are commonly used in a variety of general filtration and sample preparation applications. For sterile and general filtration applications, our unique, modified hydrophilic PVDF (Polyvinylidene Fluoride) membrane with ultra low binding properties, broad chemical and temperature resistance, and high flow rates is an excellent choice. We recommend using our hydrophilic PVDF in applications such as multi-plexed bead-based assays, the filtration of dilute protein samples, cold and hot water for injection (WFI), chemicals, aggressive solvents and sanitizing agents.

For the filtration and degassing of the solvent-based mobile phases, our portfolio includes an HPLC-certified material available in 0.2 and 0.45um, which provides assurance that the filter material will not add artifacts or extractables to the samples for analysis. The chemical compatibility of the membrane includes aggressive acids and alcohols making it useful for the filtration of both aggressive and non-aggressive solvent-based mobile phases. We do not recommend using this membrane for the filtration of acetone, DMSO, or base t;6N.

Data

China	PVDF  0.45	PVDF  0.2
Membrane thickness（um）	7-200	7-200
Bubble Point	0.6bar	1.2 bar
Water Flow Rate(ml/min at 2.1bar)	12	8

 

Millipore	PVDF  0.45	PVDF  0.2
Water Bubble Point	0.6bar	2-3.5 bar
Water Flow Rate(ml/min at 2.1bar)	12	6